2-(p-TOLUENESULFONYL)ETHANOL

PRODUCT IDENTIFICATION
CAS NO. 22381-54-0

2-(p-TOLUENESULFONYL)ETHANOL

EINECS NO.  
FORMULA CH3C6H4SO2CH2CH2OH
MOL WT. 200.25

H.S. CODE

  

TOXICITY

  
SYNONYMS 2-(4-Tolylsulfonyl)ethanol; 2-Hydroxyethyl 4-methylphenyl sulfone;
DERIVATION

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE white to off-white crystalline powder

MELTING POINT

 54 - 58 C
BOILING POINT 178 - 181 C at 0.2 mmHg
SPECIFIC GRAVITY  

SOLUBILITY IN WATER

  
pH  
VAPOR DENSITY

 

AUTOIGNITION  

REFRACTIVE INDEX

  
NFPA RATINGS  
FLASH POINT  
STABILITY Stable under ordinary conditions.

APPLICATIONS

Sulfoxide (R2SO) is any of various organic sulfur compounds having the group -SO (sulfinyl group) whereas sulfone (RSOOR) with the group -SO2 (sulfonyl group). They are derived from oxidation of sulfides. The common examples of sulfone compounds are dapsone (4,4'-sulfonylbisbenzenamine) and its derivative. Dapsone (4,4'-sulfonylbisbenzenamine) is a parent compound in preparing sulfonamide antibacterial agents such as acedapsone, acetosulfone, glucosulfone, sulfoxone and solapsone. Dapsone and its derivatives have bacteriostatic activity against a broad spectrum of gram-negative and gram-positive organisms. Dapsone is a primary treatment for Dermatitis herpetiformis and in the treatment of leprosy (Mycobacterium leprae infections) leads to apparent improvementas. It is used in the prophylaxis of falciparum malaria. It is a white crystalline powder; melting point 175 - 180C; insoluble in water and vegetable oils. Dapsone is also widely used in polymer industry as a cross linkage agent in manufacturing polysulfone amide engineering plastics. Sulfone-containing engineering plastics are thermally stable and have high resistance property to acids and alkalis. Tazobactam is a penicillanic acid sulfone derivative which acts as a beta-lactamase inhibitor similar to sulbactam. Tazobactam is used in combination with piperacillin to widen the spectrum of activity. Sulfone class compounds which have a sulfonyl group attached to two carbon atoms are active as an antibiotic.

Organosulfone compounds are widely used in refineries, steamcrackers, aromatic extraction and petrochemical manufacturing as they acts as;

  • Hydrotreating catalysts
  • Initial catalyst improvers
  • Sulfur sources
  • Catalyst presulfiding
  • Natural gas sulfur recovery

Organosulfone compounds are also used in;

  • Organic synthesis as organosulfur sources into target organic molecules for the manufacture of pharmaceuticals, adhesives biocides and agricultural products.
  • Polymer production
  • Lubricant and fuel additives for extreme pressure functionality
  • Extraction and reaction solvent
  • Metal treatment
  • Fungicide
SALES SPECIFICATION

APPEARANCE

 clear to yellowish liquid
ASSAY

98.0% min

MELTING POINT 54 - 58 C
TRANSPORTATION
PACKING 25kgs in bag
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XN, Risk Phrases: 22-38, Safety Phrases: 26-28-36/37/39