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| TIXOCORTOL PIVALATE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 55560-96-8 (Pivalate), 61951-99-3 (Parent) |
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| EINECS NO. | 259-706-4 | |
| FORMULA | C26H38O5S | |
| MOL WT. | 462.64 | |
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H.S. CODE |
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TOXICITY |
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| SYNONYMS | Tixocortol 21-pivalate; | |
| S-(11beta,17-Dihydroxypregn-4-ene-3,20-dione) 21-(thiopivalate); (11beta)-21-((2,2-Dimethyl-1-oxopropyl)thio)-11,17-dihydroxypregn-4-ene-3,20-dione; S-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14, 15,16- decahydro- 1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanethioate; | ||
| DERIVATION | ||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | white crystalline powder | |
| MELTING POINT | 195 - 200 C | |
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| SOLUBILITY IN WATER | ||
| pH | ||
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AUTOIGNITION |
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NFPA RATINGS |
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REFRACTIVE INDEX |
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| FLASH POINT |
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| STABILITY |
Stable under ordinary conditions. | |
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GENERAL DESCRIPTION & APPLICATIONS |
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| Tixocortol is a thiol derivative of hydrocortisone. Hydrocortisone derivatives are used primarily for their anti-inflammatory in allergic rashes, eczema and certain other inflammatory conditions. It is used as an immunosuppressive in the treatment of allergic and dermatologic disorders, adrenocortical insufficiency and many other disorders. | ||
| SALES SPECIFICATION | ||
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APPEARANCE |
white crystalline powder | |
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IDENTIFICATION |
pass test A (IR), B (HPLC) |
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ASSAY |
97.0% max |
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MELTING POINT |
150 - 200 C |
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| SPECIFIC ROTATION | +145° +/- 2° | |
| LOSS ON DRYING | 0.5% max | |
| RESIDENT ON IGNITION | 0.2% max | |
| RELATED SUBSTANCES | 4.5% max | |
| TRANSPORTATION | ||
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| OTHER INFORMATION | ||
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