PTEROSTILBENE

PRODUCT IDENTIFICATION
CAS NO. 537-42-8 ((trans-)
441351-32-2 (cis-)

PTEROSTILBENE 

EINECS NO.  
FORMULA C16H16O3
MOL WT. 256.30

H.S. CODE

  

TOXICITY

  
SYNONYMS 4-(2-(3,5-Dimethoxyphenyl)ethenyl)phenol;
(E)-(2-(3,5-dimethoxyphenyl)ethenyl)phenol; (E)-3',5'-Dimethoxy-4-dtilbenol; 3,5-Dimethoxy-4'-hydroxy-trans-stilbene; 4-[(E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol; 3',5'-Dimethoxy-4-stilbenol;
DERIVATION

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

off-white crystalline powder

MELTING POINT

85 - 88 C

BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER Insoluble (DMSO: 20 mg/ml)
pH  
VAPOR DENSITY  

AUTOIGNITION

 

NFPA RATINGS

  

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS
Resveratrol (3,5,4'-trihydroxystilbene) is a non-flavonoid polyphenolics compound found highly in the skin of red grapes and as a constituent of red wine. It is also found in teas, berries and peanuts. Resveratrol is a compound of stilbene structure (and is responsible for the principle coloring of the plants. Resveratrol is created by plants as a phytoalexin (plant's defense arsenal) against bacteria and fungi. It is marketed as a nutritional supplement that shows health-giving antioxidant effects such as anti-cancer, antiviral, and anti-aging. Resveratrol inhibits COX-1 enzyme and demonstrates anti-inflammatory effects. It is a platelet aggregation inhibitor to block the adhesion of blood cells to vessel walls and therefore prevents heart disease and cerebral apoplexy.  It exists as two structural isomers: cis- (Z) and trans- (E),

Piceatannol or 3,4,3',5'-tetrahydroxy-trans-stilbene is a phenolic that is structurally related to resveratrol. Piceatannol has one more hydroxyl group at 3' position. It is a metabolite of resveratrol and is found in red wine. Pterostilbene (3,5-Dimethoxy-4'-hydroxy-trans-stilbene) is an analog of resveratrol. The two phenolic hydroxyl groups among three are converted to methyl ethers. Some reports say that the ethers enhance antioxidant effects. Pterostilbene is also know as a Hypoglycemic agent and Apoptosis Inducer. Some examples of Apoptosis Inducer include:

Product

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5-(p-Bromobenzylidine)-α-isopropyl-4-oxo-2-thioxo-3-thiozolidineacetic Acid

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Borrelidin 7184-60-3
Brefeldin A 20350-15-6
Bufalin 465-21-4
6-(4-Hydroxy-3-tricyclo(3.3.1.1(3,7))dec-1-ylphenyl)-2-naphthalenecarboxylic acid 125316-60-1
1-[4-(Furo[2,3-b]quinolin-4-ylamino)phenyl]ethanone 479077-76-4
Carboxyatractylate 35988-42-2
Dimethyloxoxanthene acetic acid 117570-53-3
Fluticasone propionate 80474-14-2
Imiquimod 99011-02-6
Neocarzinostatin 9014-02-2
Nutlin-3 548472-68-0
Pterostilbene 537-42-8
SALES SPECIFICATION

APPEARANCE

off-white crystalline powder
ASSAY

98.0% min (HPLC)
TRANSPORTATION
PACKING
 
HAZARD CLASS 9 (Packing Group: 3)
UN NO. 3077
OTHER INFORMATION
Hazard Symbols: XI, N, Risk Phrases: 41-51/53, Safety Phrases: 26-39-61