ZINC GLUCONATE

ZINC GLUCONATE
PRODUCT IDENTIFICATION
CAS NO.	4468-02-4
EINECS NO.	224-736-9
FORMULA	C₁₂H₂₂O₁₄Zn.3H₂O
MOL WT.	455.68
H.S. CODE	2918.16
TOXICITY	Oral rat LD50: > 5,000 mg/kg
SYNONYMS	Gluconato de Zinc; 葡萄糖酸锌;
DERIVATION
CLASSIFICATION	GLUCONATES /
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE	white to off-white powder or granules
MELTING POINT
BOILING POINT
SPECIFIC GRAVITY
SOLUBILITY IN WATER	100 g/l
pH	5.5 - 7.5 (1% Sol.)
VAPOR DENSITY
AUTOIGNITION
NFPA RATINGS
REFRACTIVE INDEX
FLASH POINT
STABILITY	Stable under ordinary conditions
APPLICATIONS
Zinc is an essential mineral having a role in the maintenance of the body's nervous and immune systems (T-cell function). This mineral is involved in the biochemical reactions as an antioxidant in the healing process and develops normal tissues Zinc is a cofactor in enzymatic reactions such as protein synthesis polymerases and in carbonic acid anhydrase. Zinc maintains the body's alkaline balance. Zinc finger, a structural domain found in many gene-regulatory proteins, is a component of hydrophobic hormones acting stabilizing the biomembrane structures and cell membrane metabolism. Zinc deficiencies may result in prolonged wound healing, delayed sexual maturation, mental lethargy, skin changes, and susceptibility to infections. Gluconate and citrate forms are mainly used as zinc supplements. They are easily absorbed by the body. Zinc Gluconate can be formulated in pharmaceuticals, and foods as a zinc supplement. Zinc Gluconate is used as an ingredient to treat common cold and various hygienic products.
SALES SPECIFICATION
USP
APPEARANCE	white to off-white powder or granules
IDENTIFICATION	pass (Test A, Test B)
ASSAY	98.0 - 102.0% (Anhydrous Basis)
ZINC CONTENT	13.9 - 14.6 %
CHLORIDE	0.05% max
SULFATE	0.05% max
ARSENIC	3ppm max
CADMIUM	5ppm max
LEAD	10ppm max
WATER	11.6% max
REDUCING MATTERS	1.0% max
pH	5.5 - 7.5 (1% Sol.)
OVI	pass test (Organic Volatile Impurities)
TRANSPORTATION
PACKING	50kgs in fiber drum
HAZARD CLASS
UN NO.
OTHER INFORMATION
Gluconic acid is a polyhydroxycarboxylic acid with six carbon length. It is derived from glucose by oxidation of the aldehyde group on the C-1 to a carboxyl group. It is abundant in plants, fruits and other foodstuffs. Commercially the physiological d-form gluconic acid is prepared by fermentation process. It has a carboxylic group and five hydroxy groups, and thus is a good chelator particularly in alkaline conditions. Chelation is a chemical combination with a metal in complexes in which the metal is part of a ring. Organic ligand is called chelator or chelating agent, the chelate is a metal complex. The larger number of ring closures to a metal atom is the more stable the compound. Chelation is applied in metal complex chemistry, organic and inorganic chemistry, biochemistry, and environment protection. It is used in chemotherapeutic treatments for metal poisoning. Chelating agents offers a wide range of sequestrants to control metal ions in aqueous systems. By forming stable water soluble complexes with multivalent metal ions, chelating agents prevent undesired interaction by blocking normal reactivity of metal ions. Heavy metals are chelated in alkaline solution and their interferences are eliminated gluconic acid. Concentrated gluconic acid solution contains certain lactone structure, a neutral cyclic ester, showing antiseptic property. Gluconic acid and its derivatives (salts or esters) are used in the formulation of pharmaceuticals, foods, and cosmetics as mineral supplements to prevent the deficiency and as buffer salts. They are used as ingredients in various hygienic products. In industrial applications, they are used for scale removal in metal cleanings, industrial and household cleaning compounds including mouth washer, metal finishing, water treatments, and as paper and textile auxiliaries.