PRODUCT IDENTIFICATION

H.S. CODE

TOXICITY

CLASSIFICATION

Disinfectant, Thiazoline, Fungicide, Bactericide, Preservative

EXTRA NOTES

PHYSICAL AND CHEMICAL PROPERTIES

Clear light amber liquid

AUTOIGNITION

NFPA RATINGS

Health hazard: 3, Fire: 0, Reactivity Hazard: 0

REFRACTIVE INDEX

Stable under ordinary conditions. Light sensitive

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

http://apps.kemi.se/
Isothiazolines are used as preservatives in the paint industry, where they serve to protect the product from fungal and mould attacks. One of the more common products of this kind used to be Kathon®, a 1.5%-aqueous solution consisting of 1 part methylisothiazolinone (CAS No 2682-20-4), and 3 parts of chloromethylisothiazolinone (CAS No 26172-55-4). This mixture can also be identified with a specific CAS No, 55965-84-9. To avoid risk of allergy the much weaker 1,2-benzisothiazolinone (commonly called BIT) is used. This is above all used as a preservative in latex paints. These substances are used in paint, adhesives, jointing compounds, cutting fluids and detergents. Paint, adhesive and detergents are products sold for both professional and consumer use.

http://ec.europa.eu/
Kathon¢â 886 Biocide (current process) is defined as a combination of the two active ingredients produced by an integrated production process, resulting in an approximate total of 14% active ingredients, 16% magnesium nitrate, 10% magnesium chloride and 62% water.
The "mixture of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-one with magnesium chloride and magnesium nitrate" is currently regulated as a preservative in the cosmetic directive (76/768/EEC) in annex VI, part 1, entry 39 with the maximum authorized concentration 0.0015% (15 ppm) of the mixture. The submission describes Kathon¢â CG as cosmetic grade at 1.5% active ingredient stabilized with magnesium nitrate. It is the formulated product sold to customers for cosmetic applications. Kathon¢â CG is a cosmetic preservative. The main uses are rinse-off products, such as shampoos, conditioners, gels and surfactants. The EU use concentration is a maximum of 15 ppm a.i. for rinse-off and leave-on products. However, the manufacturers recommend a maximum level of 7.5 ppm a.i. (0.05% by weight of product as supplied) for leave-on products. The manufacturers recommend CMI/MI as a preservative in shower gels, body washes, bubble baths, liquid soaps, shampoos, hair conditioners and wipes. The CMI/MI mixtures have wide applications in household (domestic) and industrial products.

Local:
Isothiazolinones  containing sulfur atom (S),  nitrogen (N), oxygen (O) at 3 position and  hydrogen (H) can find application for making broad-spectrum biocides and preservatives  such as  antiseptic agents,  bactericides, slimicides, and   fungicides.    The biggest application is in paint industry especially marine antifouling agent. They are also used in adhesives, cutting oils, water systems, cosmetics, household goods and wound protectant for pruning cuts. They are also used as pulp and wood impregnating agents as well as in leather, fur and polymer process. It is known to cause allergy and chemical burn if high concentration is used in personal care products and cosmetics.

The list of isothiazolinones include  

APPEARANCE

Clear light amber liquid

ASSAY

14.0 - 14.5%

CMIT

10.1 - 11.3%

MIT

3.0 - 4.2%

SPECIFIC GRAVITY

1.26 - 1.32

pH  VALUE

1.0 - 4.0

PRICE INFORMATION