APIGENIN (4',5,7-TRIHYDROXYFLAVONE)

APIGENIN
PRODUCT IDENTIFICATION
CAS NO.	520-36-5
EINECS NO.	208-292-3
FORMULA	C₁₅H₁₀O₅
MOL WT.	270.24
H.S. CODE
TOXICITY
SYNONYMS	Naringenin chalcone; 5,7,4'-Trihydroxyflavone;
4',5,7-Trihydroxyflavone; 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone; 5,7-Dihidroxi-2-(4-hidroxifenil)-4-benzopirona; 5,7-Dihydroxy-2-(4-hydroxyphényl)-4-benzopyrone;
CLASSIFICATION	NATURAL COLORANT / ANTIOXIDANT / FLAVONES /
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE	yellow crystalline powder
MELTING POINT	315 C
BOILING POINT
SPECIFIC GRAVITY
SOLUBILITY IN WATER	Insoluble (soluble in DMSO, slightly soluble in hot ethanol)
pH
VAPOR DENSITY
REFRACTIVE INDEX
NFPA RATINGS
AUTOIGNITION
FLASH POINT
STABILITY	Stable under normal conditions
GENERAL DESCRIPTION & APPLICATIONS
Apigenin is a bioflavone, considered to have a bioactive effect on human health as antioxidant, radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, immunity system modulater.
SALES SPECIFICATION
APPEARANCE	yellow crystalline powder, odorless
ASSAY	80.0% min ( 98.0% 95.0%, 90.0% min)
RESIDUE ON IGNITION	2.0% max
LOSS ON DRY	5.0% max
HEAVY METALS	10ppm max
LEAD	10ppm max
ARSENIC	2ppm max
SOLVENTS RESIDUE	1000ppm max (ethanol)
PESTICIDES RESIDUE	100ppb max
MICROBIOLOGICALS	Total Aerobic: 1000 CFU/g max E. Coli: negative Salmonella: Negative Mold and Yeast: 100 CFU/g
TRANSPORTATION
PACKING
HAZARD CLASS
UN NO.
OTHER INFORMATION
`Hazard Symbols: , Risk Phrases:`36/37/38`, Safety Phrases:` 26-36
GENERAL DESCRIPTION OF FLAVONOID
Flavonoid is any member of a class of widely distributed biological natural products containing aromatic heterocyclic skeleton of flavan (2-Phenylbenzopyran) but no nitrogen in plants. Generally, flavonoids are biological pigments providing colours from red to blue in flowers, fruit and leaves. Besides their coloring in plants, flavonoids have important roles in the growth and development of plants; protection against UV-B radiation; forming antifungal barriers; antimicrobial, insecticidal and oestrogenic activities; plant reproduction. Flavonoids also exhibit a wide range of biological properties including anti-microbial, insecticidal and oestrogenic activities. Flavonoids are usually classified into main 6 subgroups as below plus flavans, neoflavonoids, flavonols, aurons, catechins according to the structural patterns. Flavonols (Hydroxy derivatives of flavone): Fisetin, Galangin, Kaempferide, Kaempferol, Morin, Myricetin, Myricitrin, Quercetin, Quercetrin, Rhamnetin, Robinin, Rutin, Spirenoside Flavones (skeleton: 2-phenylchromen-4-one): Apigenin, Baicalein, Chrysin, Diosmetin, Diosmin, Flavone, Luteolin, Rpoifolin,Tangeretin, Techtochrysin, Rhamnazin, Nobiletin, Natsudaidain. Isoflavones (skeleton: 3-phenylchromen-4-one): Daidzin, Genistein, Irilone, Luteone, Prunetin, Pratensein, Flavonones (derivation by reduction of the 2(3) C=C bond): Eriodictyol, Hesperidin, Hesperetin, Likvirtin, Naringin; Naringenin; Pinocembrin Flavanols (derivation by reduction of the keto group):(+)-Catechin, (+)-Gallocatechin, (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), (-)-Epicatechin 3-gallate (ECG), (-)-Epigallocatechin 3-gallate (EGCG), Theaflavin, Theaflavin 3-gallate, Theaflavin 3'-gallate, Theaflavin 3,3' digallate, Thearubigins Anthocyanidins (aglycones of the glycoside anthocyanins): Apigeninidin, Cyanidin, Delphinidin, Diosmetinidin, Guibourtinidin, Fisetinidin, Luteolinidin, Malvidin, Pelargonidin, Peonidin, Robinetinidin, Tricetinidin, Capensinidin, Petunidin, Europinidin, Aurentinidin, Columnidin, 5-Desoxy-malvidin, 5-Desoxy-peonidin, Hirsutinidin, Rosinidin
PRICE INFORMATION