NIACINAMIDE

PRODUCT IDENTIFICATION
CAS NO.

98-92-0

NIACINAMIDE

EINECS NO. 202-713-4
FORMULA

C6H6N2O

MOL WT.

122.13

H.S. CODE

 2936.29

TOXICITY

 Oral rat LD50: 3500 mg/kg
SYNONYMS 3-Pyridinecarboxamide; Nicotinamide; Propamine A;
¥â-Pyridinecarboxamide; Nicosylamide; Nicotamide; Nicotilamide; Nicotine acid amide; Nicotinic acid amide; Nicotinic amide; Nicotylamide; Nicovit; Nicovitina; Nikotinamid; Niocinamide; 3-carbamoyl-Pyridine; Vitamin B; Vitamin B3; 3-Carbamoylpyridine; 3-Pyridinecarboxylic acid amide; Picolinamide; Niamide; Nicamide; Nicogen; Nicomidol; Nicota; Nicotililamido; Nicotinsaureamid; Nicotol; Nicovel; Nicovitol; Nicozymin; Vitamin PP; Witamina PP; Amid kyseliny nikotinove; Amnicotin; Norcholine; Amid Kyseliny Nikotinove (Czech); M-(Aminocarbonyl)Pyridine; Delonin Amide; Nicotinsaureamid (German); Nikotinsaeureamid (German);
DERIVATION

beta -picoline or quinoline ¡ç coal tar

CLASSIFICATION

VITAMINS /

 

Niacin (also called Nicotinic Acid) and Niacinamide (also called Nicotinamide), two compounds of water-soluble vitamin B complex, are active in the metabolism of body. Chemically they are 3-Pyridinecarboxylic acid and 3-Pyridinecarboxamide respectively. Commercially, niacin is obtained from beta -picoline or from quinoline, which are both obtainable from coal tar. Niacinamide, more water soluble, is the amide form of niacin. When an amide molecule attaches itself to niacin, it becomes niacinamide. The B vitamins niacin and niacinamide are known as preventives of pellagra,. Niacin is interchangeable in metabolism with its amide, niacinamide . Nicotinamide is hydrolyzed to the acid in the digestive tract of non-ruminants. After absorption in the mucosa, the amide is formed again. In the rumen of ruminants, nicotinamide is converted in a short time to nicotinic acid. Nicotinamide and nicotinic acid are therefore equivalent in action in the case of farm animals. These are key ingredients in animal feed and animal feed premixes as these contribute to numerous metabolic reactions  as hydrogentransferring coenzymes. Niacin acts to reduce plasma cholesterol, as a vasodilator and to treat pellagra.  Niacin is used for the prophylaxis. Their derivatives are used for these effects.

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

White to off white powder

MELTING POINT 130 - 133
BOILING POINT 150 - 160 C
SPECIFIC GRAVITY 1.4
SOLUBILITY IN WATER Soluble
pH  
VAPOR DENSITY  

AUTOIGNITION

 

NFPA RATINGS

 Health: 1 Flammability: 1 Reactivity: 0

REFRACTIVE INDEX

 

FLASH POINT

 

STABILITY Stable under ordinary conditions

APPLICATIONS

feed additive, pharmaceuticals, food enrichment, animal mixes for livestock
SALES SPECIFICATION

BIBLIOGRAPHY

USP

APPEARANCE

White to off white powder
IDENTIFICATION

Pass Test
ASSAY

98% min
LOSS ON DRYING

0.5% max
MELTING RANGE

128 - 131 C
RESIDUE ON IGNITION

0.1% max
HEAVY METALS

20ppm max
SULFATE

0.02% max
CHLORIDE

0.025% max

PARTICLE SIZE

99% (pass 40mesh)
TRANSPORTATION
PACKING
25kgs in Bag,
HAZARD CLASS Not regulated
UN NO.  
REMARKS