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| TIBOLONE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 5630-53-5 |
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| EINECS NO. | 227-069-1 | |
| FORMULA | C21H28O2 | |
| MOL WT. | 312.45 | |
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H.S. CODE |
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TOXICITY |
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| SYNONYMS | 17-Hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one; | |
| (7alpha,17alpha)-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one; Tibolonum; 7alpha-methyl-17alpha-ethynyl-17beta-hydroxy-19-norandrost-5(10)-en-3-one; Tibolona; 7alpha-methyl-17alpha-ethynyl-17beta-hydroxyestr-5(10)-en-3-one | ||
| DERIVATION |
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | white to off-white crystalline powder | |
| MELTING POINT | 163 - 169 C | |
| BOILING POINT |
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| SPECIFIC GRAVITY |
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| SOLUBILITY IN WATER |
practically insoluble (soluble in chloroform, methanol) |
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| pH | ||
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AUTOIGNITION |
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NFPA RATINGS |
Health: 2 Flammability: 0 Reactivity: 0 | |
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REFRACTIVE INDEX |
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| FLASH POINT |
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| STABILITY |
Stable under ordinary conditions |
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APPLICATIONS |
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| Tibolone
is an anabolic steroid with moderate androgenic, estrogenic,
and progestogenic properties. It is utilized in the treatment of menopausal
and postmenopausal symptoms and osteoporosis of postmenopausal
women; administered orally. Members of anabolic steroids include
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| SALES SPECIFICATION | ||
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APPEARANCE |
white to off-white crystalline powder | |
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IDENTIFICATION |
Passes Test A(IR), B(HPLC) |
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ASSAY |
98.0
- 102.0%
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OPTICAL ROTATION |
+103° ~ +130° | |
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RESIDUE ON IGNITION |
0.1% max |
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MELTING POINT |
163 - 169 C |
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LOSS ON DRYING |
0.5% max |
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| TRANSPORTATION | ||
| PACKING |
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| HAZARD CLASS | ||
| UN NO. | ||
| OTHER INFORMATION | ||
| Hazard Symbols: T, Risk Phrases: 45-63, Safety Phrases: 53-26-36/37/39 | ||
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