PROSTAGLANDIN E1

PRODUCT IDENTIFICATION
CAS NO. 745-65-3

PROSTAGLANDIN E1
EINECS NO. 212-017-2
FORMULA C20H34O5
MOL WT. 354.49

H.S. CODE

TOXICITY
SYNONYMS Alprostadil; GE1; Prostaglandin E1; Prostin;
11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid; (13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost- 13-enoic acid; 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoic acid; (11alpha,13E, 15S)-11,15-dihydroxy-9-oxo-prost-13 -en-1-oic acid ; (5Z,13E)-(15S)-11alpha, 15-Dihydroxy- 9-oxoprost-13-enoate;
DERIVATION

 

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE white to yellow crystalline solid
MELTING POINT 115 - 116 C
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER
pH  
VAPOR DENSITY

 
AUTOIGNITION

 
NFPA RATINGS

REFRACTIVE INDEX

  
FLASH POINT

 
STABILITY

Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS
Prostaglandin is any member of a group of physiologically active compounds derived from unsaturated 20-carbon polyunsaturated fatty acids, primarily arachidonic acid. Prostaglandins are lipids having two long side chains and a 5 carbon ring structure. They are found in normal human semen in highest concentrations. Their activities affect the nervous system, circulation, female reproductive organs, and metabolism similar to local hormone functions But they are not classified in hormones.

Prostaglandin belongs to eicosanoids, biologically active 20-carbon substances including prostaglandins, thromboxanes, prostacyclins, and leukotrienes. Eicosanoids are oxygenated hydrophobic cytokines, small proteins that are the core of communication between immune systems. Prostaglandins, thromboxanes, prostacyclins are derived via the cyclooxygenase pathway, while leukotrienes are via 5-lipoxygenase pathway. Prostaglandins are eicosanoids having a cyclopentane ring. Prostaglandins have two double bonds typically, while leukotrienes have four.

Prostaglandins act in the cells in which they are synthesized and surrounding cells, and their actions and effects vary with concentration, hormonal environment, and cell type. Prostaglandins mediate a wide range of physiological functions, such as control of blood pressure, regulation of muscle, glandular secretion, transmission of nerve impulses, and modulation of inflammation. Specific Prostaglandins designated by adding a letter on PG (the abbreviation for prostaglandin) to indicate the type of ring structure and a numerical subscript to indicate the number of double bonds. The subscript alpha or beta indicates the three-dimensional configuration of alcoholic groups attached to the ring structures. Alpha denotes a substituent below the plane of the ring, beta, above the plane.
SALES SPECIFICATION

APPEARANCE

 white to off-white crystalline powder

ASSAY

99.0 % min
TRANSPORTATION
PACKING
HAZARD CLASS  
UN NO.
OTHER INFORMATION
Hazard Symbols: , Risk Phrases: , Safety Phrases: 22-24/25
PRICE INFORMATION

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