| CAS
NO. |
372-09-8 |
|
| EINECS
NO. |
206-743-9 |
| FORMULA |
NCCH2COOH |
| MOL
WT. |
85.06 |
| H.S.
CODE |
|
|
TOXICITY
|
|
| SYNONYMS |
Cyanoacetic Acid; Methyl and Ethyl esters; |
| Cyanessigsäure
(German); ácido cianoacético (Spanish);
Acide cyanoacétique (French); Malonic mononitrile |
|
DERIVATION
|
|
|
CLASSIFICATION
|
|
|
PHYSICAL
AND CHEMICAL PROPERTIES
|
| PHYSICAL
STATE |
white
to yellowish crystals |
| MELTING
POINT |
65
- 67 C |
| BOILING
POINT |
108
C at 15 mmHg (Decomposes) |
| SPECIFIC
GRAVITY |
1.055 |
| SOLUBILITY
IN WATER |
Soluble (soluble in ether, alcohol) |
| pH |
|
| VAPOR
DENSITY |
|
| AUTOIGNITION
|
|
| NFPA
RATINGS |
Health: 0; Flammability: 1; Reactivity: 0 |
|
REFRACTIVE
INDEX
|
|
| FLASH
POINT |
107
C
|
| STABILITY |
Stable
under ordinary conditions. Hygroscopic. |
|
GENERAL
DESCRIPTION & APPLICATIONS
|
Nitrile is any
of a family of organic compounds containing cyano group (-C¡ÕN) which is attached
to a carbon atom and having the general formula RC¡ÕN. Their names are
corresponding to carboxylic acids by changing '-ic acid' to '-onitrile', or
'-nitrile', whichever preserves a single letter o. Examples are acetonitrile
from acetic acid and benzonitrile from benzoic acid. Pendant nitriles are often
named as ¡°cyano¡± substituents. Cyanoacetic acid, the half
nitriled-malonic acid, and its esters are basic chemical intermediates for
the production of;
- Malonates
- Barbitals
- Caffeine,
Betaine, Vitamin B
- Pharamceuticals
- Glycine
- Surfactancts
- Agrochemicals
- Dyestuffs
- Adhesives
- Indigo
dyes
- Herbicides
- Engineering plastics
Although nitriles don't have a carbonyl group, they are often considered as
derivatives of carboxylic acids. Nitrile undergoes acid hydrolysis to form a
carboxylic acid. Nitrile is reduced to form amine in the presence of nickel
catalyst. Grignard reagents add to nitriles, forming a relatively stable imino
derivative which can be hydrolyzed to a ketone. Metaloimine is hydrolyzed to
give beta-ketoester. Nitrile undergoes a sequence of nucleophilic additions with
an alcohol under acid catalysis, called nitrile alcoholysis. Nitriles are
hydrolyzed to carboxylic acids, alcoholyzed to esters, reduced to amines,
cyclyzed to pyridine derivatives.
|
| SALES
SPECIFICATION |
|
APPEARANCE
|
white to yellowish
crystals |
|
PURITY
|
99.0%
min
|
|
MOISTURE
|
0.1%
max
|
ACIDITY |
0.1%
max
|
| TRANSPORTATION |
| PACKING |
|
| HAZARD
CLASS |
8
(Packing Group: II) |
| UN
NO. |
3261 |
| OTHER
INFORMATION |
|
Hazard
Symbols: C, Risk Phrases: 22-31-34,
Safety Phrases: 26-36/37/39-45 |