| 5-FLUOROOROTIC ACID | ||
|
PRODUCT IDENTIFICATION |
||
| CAS NO. | 703-95-7 |
|
| EINECS NO. | 211-876-0 | |
| FORMULA | C5H3FN2O4 | |
| MOL WT. | 174.09 | |
|
H.S. CODE |
2933.59 | |
| TOXICITY |
|
|
| SYNONYMS | 5-Fluorouracil-4-carboxylic acid; | |
| 5-Fluoruracil-4-carbonsäure (Dutch); ácido 5-fluorouracilo-4-carboxílico (Spanish); Acide 5-fluorouracile-4-carboxylique (French); 5-FOA; 1,2,3,6-Tetrahydro-2,6-Dioxo-5-Fluoro-4-Pyrimidinecarboxylic Acid; | ||
|
DERIVATION |
|
|
|
CLASSIFICATION |
||
|
PHYSICAL AND CHEMICAL PROPERTIES |
||
| PHYSICAL STATE | white to pale yellow powder | |
| MELTING POINT | 268 - 278 C | |
| BOILING POINT | ||
| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER |
Sparingly soluble |
|
| pH | ||
| VAPOR DENSITY |
|
|
|
AUTOIGNITION |
||
|
NFPA RATINGS |
Health: 2; Flammability: 0; Reactivity: 0 | |
|
REFRACTIVE INDEX |
||
| FLASH POINT |
|
|
| STABILITY |
Stable under ordinary conditions. |
|
|
APPLICATION |
||
| 5-Fluoroorotic Acid is a selective agent in yeast genetics such as identification of mutant yeast strains, yeast 2-hybrid system and gene replacement. It isolates orotidine-5'-monophosphate decarboxylase gene (pyrF). | ||
| SALES SPECIFICATION | ||
|
APPEARANCE |
white to pale yellow powder | |
|
PURITY (HPLC) |
99.0% min | |
|
LOSS ON DRYING |
1.0% max | |
| TRANSPORTATION | ||
| PACKING |
|
|
| HAZARD CLASS | ||
| UN NO. | ||
| OTHER INFORMATION | ||
| Hazard Symbols: XI, Risk Phrases: 22-36/37/38, Safety Phrases: 26-36 | ||
| GENERAL DESCRIPTION OF OROTIC ACID | ||
| Orotic acid:
Uracil-6-carboxylic acid, is an intermediate in the metabolism of pyrimidine
nucleotides. Naturally
occurring derivatives are components of nucleic acids: cytosine, thymidine, and
uracil).
Orotidine: a nucleoside, orotic acid N1 is linked to the C1 of ribose. Orotidine 5'-phosphate: an intermediate in pyrimidine nucleotide biosynthesis. They are used as a cosmetic ingredient, in medicine, as a feed supplement and in biochemical research. |
||
