S-(+)-1,3-BUTANEDIOL

PRODUCT IDENTIFICATION
CAS NO. 24621-61-2

S-(+)-1,3-BUTANEDIOL
EINECS NO. 246-363-0
FORMULA C4H10O2
MOL WT. 90.12

H.S. CODE

  

TOXICITY

 
SYNONYMS (S)-1,3-butanediol; (S)-(+)-1,3-Butylene glycol;

DERIVATION

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE

clear liquid
MELTING POINT 0 C
BOILING POINT 107 - 110 C at 23 mm Hg
SPECIFIC GRAVITY 1.005
SOLUBILITY IN WATER Soluble
pH  
VAPOR DENSITY

 

AUTOIGNITION

  

NFPA RATINGS

  

REFRACTIVE INDEX

 1.4385 - 1.4405
FLASH POINT

121 C
STABILITY

Stable under ordinary conditions. Hygroscopic.

GENERAL DESCRIPTION

Chiral amino alcohols and their N-protected derivatives (Cbz, t-Boc, and Fmoc) are versatile building blocks, auxiliaries, ligand or resolving agent in asymmetric synthesis for biological research and pharmaceutical applications such as antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV activities. They are used in the synthesis of beta-blockers, HIV protease and ACE inhibitors, chiral auxiliaries and catalytic enantioselective ligands. Their derivatives include the forms of;
  • C-terminal peptibiols
  • Amphiphylic antibacterial peptides
  • Oligocarbamates
  • Analogs of peptides
  • Aziridines, Halogen aminoalkyls
  • Enantiomerical alpha-alkyl mono and diamines
  • Enantiomerical beta-substituted amines
  • Enantiomerical beta-amino acids beta-amino sulfoxides, beta-amino sulfides and beta-amino thiols.
  • The precursors of diverse compounds such as statines, sphingolipides and peptide isosteres.
(S)-1,3-butanediol is an effective diol for symmetric chiral applications such as chiral auxiliaries, building blocks, chiral ligands.
SALES SPECIFICATION

APPEARANCE

white crystalsclear liquid

CHEMICAL PURITY

 98.0% min

OPTICAL PUIRTY

 98.0% min e.e.
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XN, Risk Phrases: 16-36/37/38, Safety Phrases: 26-36
Optical Rotation: +29° ~ +32° (C=1 in EtOH)