(R)-(+)-1,1'-BI-2-NAPHTHOL [(R)-BINOL]

(R)-(+)-1,1'-BI-2-NAPHTHOL

PRODUCT IDENTIFICATION

CAS NO.

18531-94-7

(R)-(+)-1,1'-BI-2-NAPHTHOL

EINECS NO.

FORMULA C₂₀H₁₄O₂

MOL WT. 286.33

H.S. CODE

TOXICITY

SYNONYMS R-(+)-2,2'-Dihydroxy-1,1'-dinaphthyl;

(R)-(+)-1,1'-Binaphthalene-2,2'-diol; (R)-Binol; (+)-2,2'-Dihydroxy-1,1'-dinaphthyl;

DERIVATION

CLASSIFICATION

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

off-white crystals

MELTING POINT 210 - 212 C

BOILING POINT

SPECIFIC GRAVITY

SOLUBILITY IN WATER

VAPOR DENSITY

AUTOIGNITION

NFPA RATINGS

Health: 2 Flammability: 0 Reactivity: 0

REFRACTIVE INDEX

FLASH POINT

STABILITY

Stable under ordinary conditions. Hygroscopic.

GENERAL DESCRIPTION & APPLICATION

1,1'-Bi-2-naphthol (BINOL) is a chiral ligand widely used in asymmetric synthesis.T he specific rotation of the two enatiomers is +/- 35.5° (c=1 in THF). BINOL is the starting material to prepare BINAP (2,2'-bis(diphenylphosphino)-1,1'-binaphthyl), one of the most influential chiral ligand to various transition metals. Two naphthyl groups linked by a single bond with diphenylphosphino groups. This chiral structure of BINOL and BINAP enable highly enantioselective reactions in asymmetric transformations including hydrogenation, hydroformylation, isomerisation of allyls, reduction of aryl ketones, hydrosilylation, hydroboration, allylic alkylation and the asymmetric Heck reaction.

BINOL	CAS RN.
(R)-(+)-1,1'-Bi(2-naphthol)	18531-94-7
(S)-(-)-1,1'-Bi(2-naphthol)	18531-99-2
(R)-(-)-1,1'-Bi-2-naphthol bis(trifluoromethanesulfonate)	126613-06-7
(S)-(+)-1,1'-Bi-2-naphthol bis(trifluoromethanesulfonate)	128544-05-8
(R)-(-)-1,1'-Bi-2-naphthyl diacetate	101758-48-9
(R)-(-)-1,1'-Bi-2-naphthyl dimethanesulfonate	871231-48-0
(S)-(+)-1,1'-Bi-2-naphthyl dimethanesulfonate	871231-47-9
(R)-(-)-1,1'- Bi-2-naphthyl ditosylate	137568-37-7
(S)-(+)-1,1'-Bi-2-naphthyl ditosylate	128544-06-9
(R)-(+)-3,3'-Bis(3,5-bis(trifluoromethyl)phenyl)-1,1'-bi-2-naphthol	756491-54-0
(S)-(–)-3-3'-Bis(3,5-bis(trifluoromethyl)phenyl)-1,1'-bi-2-naphthol	849939-13-5
(R)-(+)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene	173831-50-0
(S)-(-)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene	142128-92-5
(R)-3,3'-Bis(triphenylsilyl)-1,1'-bi-2-naphthol	111822-69-6
(R)-(+)-3,3'-Dibromo-1,1'-bi-2-naphthol	111795-43-8
(R)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol	65283-60-5
(S)-(+)-6,6'-Dibromo-1,1'-bi-2-naphthol	80655-81-8
(S)-(-)-3,3'-Dibromo-1,1'-bi-2-naphthol	119707-74-3
(R)-(+)-6,6'-Dibromo-2,2'-bis(methoxymethoxy)-1,1'-binaphthalene	179866-74-1
(S)-(-)-6,6'-Dibromo-2,2'-bis(methoxymethoxy)-1,1'-binaphthalene	211560-97-3
(R)-(+)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2,2'-naphthalenediol	65355-08-0
(S)-(-)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2,2'-naphthalenediol	765278-73-7
Dipottassium (R)-3,3'-Di-tert-butyl-5,5',6,6',7,7',8,8'-octahydro-1,1'-(bi-2-naphthol)	350683-75-9
(R)-(+)-2,2'-Dimethoxy-1,1'-binaphthalene	35294-28-1
(S)-(-)-2,2'-Dimethoxy-1,1'-binaphthalene	75640-87-8
(R)-(+)-Dimethyl-2,2'-dihydroxy-1,1'-binaphthalene-3,3'-dicarboxylate	18531-91-4
(S)-(-)-Dimethyl-2,2'-dihydroxy-1,1'-binaphthalene-3,3'-dicarboxylate	69678-00-8
(R)-5,5',6,6',7,7',8,8'-Octahydro-bi-2-naphthol	65355-14-8
(S)-(-)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-bi-2-naphthol	65355-00-2
(R)-3,3'-Diphenyl-2,2'-bi(1-naphthalol	147702-13-4
(S)-3,3'-Diphenyl-2,2'-bi(1-naphthalol)	147702-14-5
(3R)-(-)-2,2'-Diphenyl-(3,3'-biphenanthrene)-4,4'-diol dichloromethane	147702-16-7
(3S)-(+)-2,2'-Diphenyl-(3,3'-biphenanthrene)-4,4'-diol dichloromethane	147702-15-6
BINAP	CAS RN
(R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene	76189-55-4
(S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene	76189-56-5
[(R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl]palladium(II) chloride	115826-95-4
(R)-(+)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl	99646-28-3
(S)-(-)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl	100165-88-6

SALES SPECIFICATION

APPEARANCE

off-white crystals

CHEMICAL PURITY

99.5% min

OPTICAL PUIRTY

99.5% min e.e.

TRANSPORTATION

PACKING

HAZARD CLASS

UN NO.

OTHER INFORMATION

Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 22-24/25
Optical Rotation: +35° ~ +36° (C=1, THF)