(2R,4R)-(-)-PENTANEDIOL

PRODUCT IDENTIFICATION
CAS NO. 42075-32-1

(2R,4R)-(-)-PENTANEDIOL
EINECS NO.

 
FORMULA C5H12O2
MOL WT. 104.15

H.S. CODE

  

TOXICITY

 
SYNONYMS (R,R)-(-)-2,4-Pentanediol;

DERIVATION

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE

white crystals
MELTING POINT 48 - 52 C
BOILING POINT 111 - 113 at 19 mm Hg
SPECIFIC GRAVITY  
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

AUTOIGNITION

  

NFPA RATINGS

  

REFRACTIVE INDEX

  
FLASH POINT

101 C
STABILITY

Stable under ordinary conditions. Hygroscopic.

GENERAL DESCRIPTION

Chiral amino alcohols and their N-protected derivatives (Cbz, t-Boc, and Fmoc) are versatile building blocks, auxiliaries, ligand or resolving agent in asymmetric synthesis for biological research and pharmaceutical applications such as antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV activities. They are used in the synthesis of beta-blockers, HIV protease and ACE inhibitors, chiral auxiliaries and catalytic enantioselective ligands. Their derivatives include the forms of;
  • C-terminal peptibiols
  • Amphiphylic antibacterial peptides
  • Oligocarbamates
  • Analogs of peptides
  • Aziridines, Halogen aminoalkyls
  • Enantiomerical alpha-alkyl mono and diamines
  • Enantiomerical beta-substituted amines
  • Enantiomerical beta-amino acids beta-amino sulfoxides, beta-amino sulfides and beta-amino thiols.
  • The precursors of diverse compounds such as statines, sphingolipides and peptide isosteres.
(R,R)-(-)-2,4-Pentanediol is an effective diol for asymmetric chiral applications such as chiral auxiliaries, building blocks, chiral ligands.
SALES SPECIFICATION

APPEARANCE

white crystals

CHEMICAL PURITY

 99.5% min

OPTICAL PUIRTY

 99.5% min e.e.
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XN, Risk Phrases: 16-36/37/38, Safety Phrases: 22-24/25
Optical Rotation: -39° ~ -41° (C=10 in CHCl3)