(1S,2S)-(+)-2-AMINO-1-PHENYL-1,3-PROPANEDIOL

PRODUCT IDENTIFICATION
CAS NO. 28143-91-1

(1S,2S)-(+)-2-AMINO-1-PHENYL-1,3-PROPANEDIOL
EINECS NO. 248-867-6
FORMULA C6H5CH(OH)CH(NH2)CH2OH
MOL WT. 167.21

H.S. CODE

 2922.19.8590

TOXICITY

 
SYNONYMS L(+)-threo-2-Amino-1-phenyl-1,3-propanediol;

(S(R',R'))-2-Amino-1-phenylpropane-1,3-diol;

SMILES

c1([C@@H]([C@@H](N)CO)O)ccccc1

CLASSIFICATION

 Amino Alcohol, Chiral Building Block

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE light yellow powder
MELTING POINT

112 - 115 C
BOILING POINT  
SPECIFIC GRAVITY  
SOLUBILITY IN WATER  
pH  
VAPOR DENSITY

 

AUTOIGNITION

  

NFPA RATINGS

 Health: 1 Flammability: 0 Reactivity: 0

REFRACTIVE INDEX

 
FLASH POINT

 
STABILITY

Stable under ordinary conditions.

GENERAL DESCRIPTION

Chiral amino alcohol possessing both amine and alcohol is a structural motif for the compounds which have important biological and pharmacological functions within the body as inhibitor of aspartyl proteases, aldose reductase, b-amyloid peptide formation, and dopamine D4 antagonists. The chiral amino alcohol also exhibits anti-inflammatory, anesthetic, antipasmodic, hepatotoxic, anti-diabetic, anti-obesity,and anti-depressant activities. Chiral amino alcohols and their N-protected derivatives (Cbz, t-Boc, and Fmoc) are versatile building blocks, auxiliaries, ligand or resolving agent in asymmetric synthesis for biological and pharmaceutical researches. applications are present in the field of antitumor, anesthetic, antipasmodic, hepatotoxic, antiinflammatory or anti-HIV activities.  Their derivatives include the forms of;

  • C-terminal peptibiols
  • Amphiphylic antibacterial peptides
  • Oligocarbamates
  • Analogs of peptides
  • Aziridines, Halogen aminoalkyls
  • Enantiomerical alpha-alkyl mono and diamines
  • Enantiomerical beta-substituted amines
  • Enantiomerical beta-amino acids beta-amino sulfoxides, beta-amino sulfides and
  • beta-amino thiols.
  • The precursors of diverse compounds such as statines, sphingolipides and peptide isosteres

Chiral amino alcohols

Product

CAS RN.
Cathine 492-39-7

(S)-(+)-Norepinephrine L-bitartrate

 636-88-4
(R)-(-)-Leucinol 53448-09-2

(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol

 716-61-0
L-2-Amino-3-methylbutan-1-ol 2026-48-4

(R)-(-)-2-Amino-1-phenylethanol

 2549-14-6

S-(+)-2-Amino-1-propanol

 2749-11-3

(S)-(+)-1-Amino-2-propanol

 2799-17-9

(R)-(-)-1-Amino-2-propanol

 2799-16-8
L-2-Amino-4-methylthiobutan-1-ol 2899-37-8

(1S,2S)-(+)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol

 2964-48-9
L-Phenylalaninol 3182-95-4

(S)-(-)-Propranolol hydrochloride

 4199-10-4

(R)-(-)-2-Amino-3-methyl-1-butanol

 4276-09-9
D-Phenylalaninol 5267-64-1

(S)-(+)-2-Amino-1-butanol

 5856-62-2

(R)-(-)-2-Amino-1-butanol

 5856-63-3

(-)-Isoproterenol hydrochloride

 5984-95-2

(R)-(+)-Propranolol hydrochloride

 13071-11-9

(S)-(+)-2-tert-Butylamino-1-phenylethanol

 14467-32-4

(R)-(-)-2-tert-Butylamino-1-phenylethanol

 14467-51-7

(1S,2S)-(+)-Thiomicamine

 16854-32-3

(S)-(+)-2-Amino-1-pentanol

 22724-81-8

(1R,2S)-(-)-2-Amino-1,2-diphenylethanol

 23190-16-1

(S,S)-(-)-2-Amino-1,2-diphenylethanol

 23190-17-2
L-(Pyrrolidin-1-yl)methanol 23356-96-9

(1S,2R)-(+)-2-Amino-1,2-diphenylethanol

 23364-44-5
2-Amino-3-methylpentan-1-ol 24629-25-2

(1S,2S)-(+)-2-Amino-1-phenyl-1,3-propanediol

 28143-91-1

(S)-(-)-3-tert-Butylamino-1,2-propanediol

 30315-46-9

(R)-(-)-2-Amino-1-propanol

 35320-23-1

(1R,2R)-(-)-Norpseudoephedrine

 37577-07-4

(2S,3R)-(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol

 38345-66-3

(1R,2R)-(-)-2-Amino-1-phenyl-1,3-propanediol

 46032-98-8

(S)-(+)-2-Benzylamino-1-phenylethanol

 51096-49-2

(1S,2S)-(+)-2-Amino-3-methoxy-1-phenyl-1-propanol

 51594-34-4

(S)-(+)-1-Dimethylamino-2-propanol

 53636-17-2
(R)-beta-Aminophenethyl alcohol 56613-80-0

(S)-2-Amino-1-phenylethanol

 56613-81-1

(R)-(+)-Atenolol

 56715-13-0

(R)-(+)-2-Amino-3-benzyloxy-1-propanol

 58577-87-0

(S)-(+)-2-(Dibenzylamino)-1-propanol

 60479-65-4
(S)-(-)-3-Amino-1,2-propanediol 61278-21-5

(R)-3-Amino-1,2-propanediol

 66211-46-9

(1S,2S)-trans-2-Aminocyclopentanol hydrochloride

 68327-04-8
D-Prolinol 68832-13-3

(1R,2S)-cis-2-(Benzylamino)cyclohexanemethanol

 71581-92-5

(1S,2R)-cis-2-(Benzylamino)cyclohexanemethanol

 71581-93-6

(2R,3S)-(-)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol

 72541-03-8

1,1-Diphenyl-L-alaninol

 78603-91-5

(R)-(+)-2-Amino-1,1-diphenyl-1-propanol

 78603-93-7

(S)-(-)-2-Amino-3-methyl-1,1-diphenyl-1-butanol

 78603-95-9

(S)-(-)-2-Amino-4-methyl-1,1-diphenyl-1-pentanol

 78603-97-1

(S)-2-(Boc-amino)-1-propanol

 79069-13-9

(S)-(-)-2-Amino-1,1,3-triphenyl-1-propanol

 79868-78-3

(R)-(-)-2-Amino-1-pentanol

 80696-30-6

(R)-(-)-2-Amino-1-hexanol

 80696-28-2

(S)-(+)-2-Amino-1-hexanol

 80696-29-3

(R)-(+)-2-Amino-3-methyl-1,1-diphenyl-1-butanol

 86695-06-9

(R)-(+)-2-Amino-1,1,3-triphenyl-1-propanol

 86906-05-0
D-Methioninol 87206-44-8

(R,R)-(+)-2-Amino-1,2-diphenylethanol

 88082-66-0

(S)-(-)-(3-Chloro-2-hydroxypropyl)trimethylammonium chloride

 101396-91-2

(S)-(-)-2-(tert-Butoxycarbonylamino)-3-cyclohexyl-1-propanol

 103322-56-1

N-Boc-(2S,3S)-(-)-2-Amino-3-methyl-1-pentanol

 106946-74-1

(R)-(-)-2-Benzylamino-1-phenylethanol

 107171-75-5

(S)-(+)-2-(N,N-Dibenzylamino)-4-methylpentanol

 111060-53-8

(S)-2-(N,N-Dibenzylamino)-3-methylbutanol

 111060-54-9
N,N-Dibenzyl-L-phenylalaninol 111060-52-7

(S)-(+)-2-Amino-3-cyclohexyl-1-propanol hydrochloride

 117160-99-3

(1S,2R)-(-)-cis-1-Amino-2-indanol

 126456-43-7

(R)-(+)-3-Benzyloxy-2-(Boc-amino)-1-propanol

 127559-33-5

(S)-(-)-2-(Boc-amino)-1,4-butanediol

 128427-10-1

(S)-(-)-2-Amino-1,1,2-triphenylethanol

 129704-13-8

(1R,2S)-(+)-cis-1-Amino-2-indanol

 136030-00-7

(1R,2S)-cis-2-Aminocyclopentanol hydrochloride

 137254-03-6

(S)-(-)-2-Amino-3,3-dimethyl-1,1-diphenyl-1-butanol

 144054-70-6

N-Boc-(S)-(-)-2-amino-1-butanol

 150736-72-4

(R)-(+)-2-Amino-4-methyl-1,1-diphenyl-1-pentanol

 161832-74-2

(S)-(-)-2-(Boc-amino)-1,5-pentanediol

 162955-48-8

(1S,2S)-(+)-trans-1-Amino-2-indanol

 163061-74-3

(1R,2R)-(-)-trans-1-Amino-2-indanol

 163061-73-2
(1S, 2S)-(+)-Pseudoephedrine glycinamide 170115-96-5

(R)-(-)-2-(Dibenzylamino)-3-phenyl-1-propanol

 307532-06-5

Norepinephrine L-bitartrate hydrate

 339091-66-6

(R)-(+)-N-Carbomethoxy-2-amino-1,1,2-triphenylethanol

 352535-67-2

N-Boc-(1R,2R)-(-)-2-amino-1-(4-nitrophenyl)-1,3-propanediol

 366487-74-3
SALES SPECIFICATION

APPEARANCE

 light yellow powder

CHEMICAL PURITY

 99.0% min

OPTICAL PURITY

 99.0% min e.e.
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-37/39
Optical Rotation: +36° ~ +38° (C=1, 1 N HCl)